|
|
aclacinomycin_S + dTDP-L-rhodinose <=> aclacinomycin_N + dTDP + H+
|
2.4.1.327
aclacinomycin-T 2-deoxy-L-fucose transferase
|
–
|
| |
MetaCyc:
RXN-14851
|
|
|
|
propionyl-CoA + malonyl-CoA + polyketide-[acp] + H+ <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoyl-[acp] + CO2 + CoA
|
2.3.1
|
–
|
| |
MetaCyc:
RXN-14846
|
|
|
|
6-[3-hydroxy-2-(3,5,7-trioxononanoyl)phenyl]-3,5-dioxohexanoate <=> 12-deoxyaklanoate + H2O
|
4.2.1
|
–
|
| |
MetaCyc:
RXN-17998
|
|
|
|
9-hydroxy-3,5,7,11,13,15,17,19-octaoxohenicosanoyl-[acp] + NADP+ <=> 3,5,7,9,11,13,15,17,19-nonaoxohenicosanoyl-[acp] + NADPH + H+
|
1.1.1
|
–
|
| |
MetaCyc:
RXN-14875
|
|
|
|
aclacinomycin_N + O2 <=> Aclarubicin + H2O2
|
1.1.3.45
aclacinomycin-N oxidase
|
–
|
| |
BRENDA:
BR50598
KEGG:
R09334
MetaCyc:
RXN-14689
|
|
|
|
aklavinone + NADP+ <=> aklaviketone + NADPH + H+
|
1.1.1.362
aklaviketone reductase
|
–
|
| |
BRENDA:
BR50595
KEGG:
R06682
MetaCyc:
RXN-14818
|
|
|
|
Aclarubicin + O2 <=> aclacinomycin_Y + H2O2
|
1.3.3.14
aclacinomycin-A oxidase
|
–
|
| |
BRENDA:
BR50611
KEGG:
R09335
MetaCyc:
RXN-14688
|
|
|
|
S-adenosyl-L-methionine + aklanonate <=> S-adenosyl-L-homocysteine + methyl_aklanonate
|
2.1.1.288
aklanonic acid methyltransferase
|
–
|
| |
BRENDA:
BR50636
KEGG:
R06680
MetaCyc:
RXN-14831
|
|
|
|
aclacinomycin_T + dTDP-2-deoxy-alpha-L-fucose <=> aclacinomycin_S + dTDP + H+
|
2.4.1.327
aclacinomycin-T 2-deoxy-L-fucose transferase
|
–
|
| |
BRENDA:
BR51044;
BS430146
KEGG:
R09332
MetaCyc:
RXN-14852
SABIO-RK:
14528
|
|
|
|
12-deoxyaklanoate + O2 <=> aklanonate + H2O
|
1.13.12
|
–
|
| |
KEGG:
R06679
MetaCyc:
RXN-14854
|
|
|
|
aklavinone + dTDP-beta-L-rhodosamine <=> aclacinomycin_T + dTDP + H+
|
2.4.1.326
aklavinone 7-L-rhodosaminyltransferase
|
–
|
| |
BRENDA:
BR51043
KEGG:
R09331
MetaCyc:
RXN-14853
|
|
|
|
9-hydroxy-3,5,7,11,13,15,17,19-octaoxohenicosanoyl-[acp] <=> 6-[3-hydroxy-2-(3,5,7-trioxononanoyl)phenyl]-3,5-dioxohexanoate + polyketide-[acp] + H2O + H+
|
4.2.1
|
–
|
| |
MetaCyc:
RXN-14874
|
|
|
|
aklaviketone <=> methyl_aklanonate
|
5.5.1.23
aklanonic acid methyl ester cyclase
|
–
|
| |
BRENDA:
BR50726
KEGG:
R06681
MetaCyc:
RXN-14844
|
|
